The Thorne Podcast

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With so much happening in the world of health and wellness, how can you separate fact from fiction? Listen to Thorne’s medical experts as they bring you the latest insights, access to exclusive interviews, and much more as the Thorne Podcast navigates the complex world of health and wellness. Here you’ll discover the newest research on diet, nutritional supplements, and lifestyle approaches to unlocking your best self.

Episodes

Wednesday Jan 13, 2021

UFC’s Anthony Smith on Training and Nutrition | PE Edition

Wednesday Jan 13, 2021

As an MMA fighter, Anthony Smith requires his body to perform at peak potential. In this special Performance Edition of the Thorne Podcast, listen as Joel Totoro, Director of Sports Science at Thorne and the UFC’s Anthony Smith talk about what goes in to the training, recovery, and nutrition regimen of a UFC athlete.

During this episode you’ll learn about:

Anthony Smith on making the jump from middleweight to light heavyweight [2:03]
- UFC Performance Institute [3:32]
Tracking nutritional and performance changes [4:30]
- Achieving nutritional balance [5:30]
Implementing change and breaking habits [6:48]
Preparing for a UFC fight [8:54]
- Tracking a MMA fighter’s stats [9:26]
Supplements for UFC training [11:23]
- Using supplements along with diet and proper training [11:48]
- Creatine and protein [12:42]
Avoiding exercise and training mistakes [13:59]
- Focus on rest and recovery, proper nutrition [14:24]
- Listen to coaching staff [15:54]
- Balance between training and recovery [16:40]
Community Questions
- How do you prefer to take your protein [18:47]
  - Protein powder with almond milk [18:57]
- How to handle injuries and downtime [19:29]
  - Learning to work around it [19:37]
- Cutting weight for UFC [20:58]
  - Recovery and rehydration [21:11]
  - Finding an ideal float weight [23:04]
- What would your ultimate UFC fantasy fight be? [24:15]
  - Royce Grace and Demian Maia [24:32]
- UFC PI Laser Pod and other training equipment [25:12]
Fight Nation Radio [25:58]

Resources to topics mentioned in this episode:

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Make sure to never miss an episode by subscribing to the show on your podcast app. You can also learn more about what we talked about by visiting Thorne.com and checking out the latest news, videos, and stories on Thorne’s Take 5 Daily blog.

Wednesday Jan 06, 2021

What Causes a Leaky Gut?

Wednesday Jan 06, 2021

Intestinal hyperpermeability, commonly called Leaky Gut Syndrome, is when the gut’s protective mucosal barrier loses its effectiveness, which allows bacteria, toxins, and unwanted molecules to “leak” into the bloodstream. In this episode of the Thorne Podcast, Dr. Frank Lipman and Dr. Robert Rountree discuss the symptoms of a leaky gut and the techniques for keeping your gut health on track.

During this episode, you’ll learn about:

Increased intestinal permeability [2:50]
- New research on intestinal permeability and gut barrier [3:40]
- Leaky gut misunderstandings [5:05]
Occurring at microscopic level [5:52]
- Leaky Gut and small intestine [6:48]
- Endotoxins [7:16]
Leaky gut, obesity, and fatty liver [8:13]
The gut and the body’s inflammatory response [8:41]
Improving the functioning of the gut wall [9:00]
- Modern life and overprocessed foods and your gut [9:40]
Medical journals on intestinal permeability [10:28]
Altered microbiome causing leaky gut? [11:31]
- Bacteriophages and your gut [12:11]
- Achieving gut balance [13:10]
- Yeast strains and the gut [14:10]
- Fungi [14:40]
Overgrowth and leaky gut [15:00]
Alcohol, anti-inflammatory drugs, and leaky gut [16:21]
High-sugar and high-carb diets [17:12]
Questions from the community [18:47]
- Why is leaky gut not more commonly discussed? [18:56]
  - The name leaky gut [19:00]
  - Using more technical terms to describe leaky gut [19:20]
  - Introduce the research on intestinal permeability [19:40]
  - Alessio Fasano [20:08]
  - Gluten and leaky gut [20:20]
- Testing gluten sensitivity [20:03]
  - Anti-gliadin antibodies [21:06]
  - Other proteins in gluten [22:14]
- How to tell if I have leaky gut [22:35]
  - Bloating, gas, irregular bowel movements [22:45]
  - Joint pain and skin rashes [23:23]
- L-glutamine supplements and gut health [24:48]
- Other supplements for gut health [25:52]
- Peptides and gut health [27:00]

Resources to topics mentioned in this episode:

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Be sure to never miss an episode by subscribing to the show on your podcast app. You can also learn more about what was talked about by visiting Thorne.com and checking out the latest news, videos, and stories on Thorne’s Take 5 Daily blog.

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Wednesday Dec 23, 2020

Understanding Gut Health and Diet

Wednesday Dec 23, 2020

Even if you don’t happen to have noticeable digestive issues, focusing on taking care of your gut’s microbiome can have a big impact on your overall health. In this episode of the Thorne Podcast, Dr. Frank Lipman and Dr. Robert Rountree explore dietary factors, supplements, and other measures for supporting optimal GI health.

During this episode you’ll learn about:

Bacteriophages and gut bacteria [2:47]
Chronic gut problems [3:30]
- Gut imbalances [4:12]
Plant lectins and your gut [4:51]
Bacterial overgrowth [5:55]
- Antibiotics [6:10]
- Small intestinal bacterial overgrowth (SIBO) [6:28]
- Herbs for gut health [7:00]
Underlying causes for SIBO [7:42]
- Gut motility disruptions [8:10]
- Dysbiosis [9:02]
Berberine supplements [9:47]
Acupuncture and gut health [11:05]
Low FODMAP diets [12:13]
- Uses for chronic bloating [12:45]
- Need to address underlying symptoms in gut [13:33]
- Elimination diets [14:28]
Gut health tests [16:16]
- Can help an individual get better understanding of their gut [17:14]
Gluten-free diets [17:57]
- Avoiding corn, wheat, dairy, so, egg, and sugar [18:03]
- Celiac disease [18:32]
Community Questions [20:38]
- What are the symptoms of an unhealthy gut? [20:46]
  - Bloating, gas, acid reflux, and discomfort [20:57]
  - Skin problems, joint aches, and brain fog [21:22]
  - Getting a stool sample test for microbiome [22:50]
- How can I clean up my gut? [24:24]
  - Fasting and anti-microbials for the gut [24:51]
  - Plant-based proteins and MediClear Plus for your gut [26:02]
  - Bone broth [27:08]
  - Collagen powders [28:08]
- Acne breakouts and your gut [29:19]
  - Taking care of your gut may help with acne [29:50]
  - Refined carbohydrates and your gut [30:05]
  - Antibiotics [30:38]

Resources to topics mentioned in this episode:

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Wednesday Dec 09, 2020

Gut Check: How Your Gut Influences Whole-Body Health

Wednesday Dec 09, 2020

The human gut comprises the intestinal tract plus a complex mix of organs, microbes, hormones, and enzymes. To better understand how this complex system interacts with so many aspects of our health, listen to Dr. Frank Lipman and Dr. Robert Rountree talk about the gut, the trillions of organisms it contains, and how it relates to your health.

During this episode of the podcast you will learn about:

The Gut: An essential ingredient in health [1:27]
Science shows there are more cells in intestines than anywhere else in the body [3:36]
Feeding the microbiome [4:05]
- The gut’s microbiome affects the brain, hormones, and other areas of health [4:30]
Protecting the gut lining [5:22]
Phages and your gut [6:33]
- Bacteriophages and gene swapping [7:07]
- Antibiotics and bacteriophages [8:12]
- Antibiotic-resistant genes [8:30]
- Bacteriophages control the types of bacteria in our gut microbiome [9:50]
Probiotics [10:43]
Prebiotics [11:10]
Studying benefits of bacteriophages [12:13]
- A new possibility for supporting gut health [13:30]
Gas, bloating, and other side effects of probiotics [14:05]
Anti-microbials [14:25]
5 R Plan for Gut Health [16:42]
Natural versions of antibiotics [18:38]
- Could have less impact on good bacteria [19:11]
Community questions [22:31]
- The gut-brain connection [22:43]
  - More nerves go from the gut to the brain than the other way around [23:00]
  - Are anxiety and depression linked to gut health? [24:15]
- Does the gut produce neurotransmitters like serotonin? [25:48]
  - Ninety percent of serotonin is made in the gut [26:13]
  - 5-HTP and gut health [27:03]

Resources to topics mentioned in this episode:

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Wednesday Dec 02, 2020

Getting Smart about Brain Health

Wednesday Dec 02, 2020

During this episode you’ll learn about:

Cognition: a growing concern [1:18]
Factors that influence cognition: stress, sleep, exercise, diet, isolation [2:23]
- Cognition could be a symptom to some imbalance in the body [3:37]
Meditation is like physical exercise for the mind [4:00]
Matthew Walker: Why We Sleep [4:27]
- Sleep is critical for mental function, helps the brain sort through memories and process information [5:06]
- Sleep allows the brain to cleanse itself [5:26]
Brain function naturally slows down as we age [6:10]
- Aging results in the brain processing information slower [7:40]
Brain fog [9:04]
- The gut-brain connection and brain fog [9:15]
- Hormonal connection to brain fog [10:21]
- Neurotransmitters and gut bacteria [11:13]
- Resetting the gut with protein powders [12:25]
Exercise and cognition [13:22]
- Can help clear the mind [14:00]
Brain derived neurotrophic factor or BDNF [14:21]
- Proteins that act as “fertilizer” for brain cells [14:30]
- Nutrients for BDNF / sulforaphane glucosinolate (SGS) [16:00]
Coffee fruit extract [17:55]
Nicotinamide riboside (NR) and resveratrol [18:56]
Questions from the community [20:32]
- What are cognitive risks for athletes? And what can we do to mitigate them? [20:44]
  - Head injuries and micro trauma[20:56]
  - Athletes could benefit from curcumin and fish oil supplements [20:56]
  - Testing for APOE2 gene [21:52]
  - CTE [22:20]
- Should I let my children play contact sports? [24:05]
  - Consider genetic testing [24:16]
  - If they are positive for APOE4, it might be best to discourage them [24:51]
  - Consider non-contact sports as alternative [25:25]
- What are some top recommended nootropics? [25:39]
  - Coffee [25:44]
  - Matcha tea [26:00]
  - Bacopa [26:15]
  - Huperzine A [26:40]
  - Phosphatidylserine [26:50]
  - Fish Oil [27:00]

Resources to topics mentioned in this episode:

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Wednesday Nov 18, 2020

The Silent Epidemic: Sleep Deprivation

Wednesday Nov 18, 2020

During this episode you’ll learn about:

Sleep deprivation and health problems [2:26]
The Sleep Deprivation Endemic [3:40]
- Even during the pandemic, people are reporting a lack of quality sleep [4:12]
- Many people aren’t falling into deep sleep [4:50]
- Poor sleep is associated with chronic stress [5:08]
Stress levels are on the rise across society for a variety of reasons [6:45]
Are home sleep tracking devices accurate? [7:10]
- Sleep labs vs sleep tracking devices [9:23]
- Home sleep devices are not medical devices, but can give a good idea of overall sleep trends [9:46]
REM sleep and deep sleep are important to sleep quality [10:47]
Correlation between blood glucose and lack of sleep [11:30]
- Blood sugar levels are high in the morning after not sleeping well [12:23]
Sleep as a rhythm disorder [13:37]
Sleep isn’t like turning off a switch [14:47]
- Sleep is a process. It requires winding down [15:00]
- Gabriel Roth’s concept of bodily rhythms [15:35]
One aspect of sleeping better is sticking to a routine [16:35]
- Go to bed and wake up at the same time each day [16:50]
- Get natural light in the morning to wake the body up [17:00]
Sleep and Aging [17:47]
- As we age, hormone production, like melatonin, is more likely to get disrupted [18:15]
- Younger people have easier time falling to sleep [18:50]
Supplements and Sleep [19:24]
- PharmaGABA [19:37]
  - Can support a calmer mood [20:16]
- L-Theanine [20:40]
- CBD [21:43]
  - Hemp Oil vs. CBD [21:51]
- Questions from the community [23:51]
  - What is the best CBD supplement for sleep [24:00]
    - Bob: Hemp Oil + because of full spectrum cannabinoids [24:10]
  - How to achieve deeper sleep [25:15]
    - CBD / hemp oil can help [25:25]
    - Deep sleep requires a comprehensive approach: lifestyle factors, healthy diet, stress management, exercise [25:50]
    - Mindfulness meditation for better sleep [26:30]
    - Magnesium for sleep [26:56]
  - Are there any natural alternative for disruptive sleep from snoring? [27:51]
    - Consult a medical professional to test for sleep apnea [28:10]
    - No magic pill for snoring [29:15]
    - Could be over-production of mucus [29:20]
    - Clean out sinuses [29:49]
    - Breath right nasal strips [30:21]

Resources to topics mentioned in this episode:

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Wednesday Nov 11, 2020

Understanding the Aging Process

Wednesday Nov 11, 2020

Dr. Frank Lipman and Dr. Robert Rountree are back to discuss everything you need to know about the aging process, including nutritional supplement strategies that can optimize aging.

During this episode, you will learn about:

Is aging a disease that can be reversed [2:25]
- While aging isn’t a disease, it can predispose you to disease [3:05]
Aging is a complicated process [5:00]
- No person ages the same – different habits lead to different outcomes [6:25]
- We use a Western medicine approach – we try to “treat” aging like we would a disease – but it’s more complicated than that [6:45]
- Having meaning, passions, and a good support system plays a big role [6:55]
Metformin and aging [7:30]
- A New England Journal of Medicine study found lifestyle changes are just as effective as medication at improving blood sugar levels [7:50]
- Clinical studies for Metformin and breast cancer [8:35]
- Study for Metformin and Aging [9:10]
- Side effects of Metformin [11:30]
Berberine [13:20]
- Doesn’t seem to inhibit mitochondria as Metformin does / can regulate gut flora / can have brain-supportive properties [13:40]
- Not a magic “aging” pill, but can be a part of an age management protocol [14:11]
Intermittent Fasting Study [18:43]
- Fasting for weight loss versus fasting for healthy aging [19:10]
- Studies show intermittent fasting improves certain biomarkers [20:35]
- Snacking and restricted eating [21:51]
Community Question: What are some red flags to look for after age 55? [25:00]
- Monitoring blood sugar [25:15]
- Brain and memory function [25:40]
- Loss of muscle mass / sarcopenia [26:05]
- Getting enough sleep as you age [27:51]

Resources to topics mentioned in this episode:

Get access to Dr. Lipman’s in-depth analysis for optimizing the natural aging process in his newest book The New Rules of Aging Well: A Simple Program for Immune Resilience, Strength, and Vitality. Order your copy today at DrFrankLipman.com.

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Be sure to never miss an episode by subscribing to the show on your podcast app. You can also learn more about what we talked about by visiting Thorne.com and checking out the latest news, videos, and stories on Thorne’s Take 5 Daily blog.

Wednesday Oct 28, 2020

How to Achieve Healthy Aging

Wednesday Oct 28, 2020

Dr. Frank Lipman, Functional Medicine Doctor and New York Times bestseller, and Dr. Robert Rountree, Functional Medicine Physician and Thorne's Chief Medical Advisor, discuss factors that influence healthy aging – a process defined as maintaining optimal mental, social, and physical well-being in an aging adult.*

During this episode you will learn about:

What things speed up aging? [3:50]
- Certain habits, such as cigarette smoking, speed up the aging process [4:05]
Oxidative stress is a major aging pathway [4:30]
- Rancid fats and free radicals [5:13]
- Free radicals accumulate and damage tissue over time [5:40]
- Damage caused to mitochondria [5:55]
Free Radical Theory of Aging [6:30]
- Some free radicals can actually be good for you [6:56]
- Antioxidants like vitamin C and zinc don’t exert the kind of activity that slows down aging [7:15]
- It depends on the kind of free radical – free radicals from toxic chemicals and cigarette smoke are the kind of free radicals that speed up aging [7:57]
Plant compounds in green tea, broccoli, turmeric, red wine, and grapes can activate the body’s internal antioxidant defenses [8:33]
You can’t eliminate oxidative stress – but you can keep it at bay [9:05]
Chinese Medicine and Ancient Wisdom [9:41]
- While a little stress can be good for the body [10:30]
- Chronic stress can be bad [10:40]
Fasting [11:00]
- Can have a positive impact on body biochemistry [11:35]
- Time-restricted eating, and 16-hour interval fasting [12:10]
- Fast-mimicking diet [12:20]
- Fasting and its impact on biomarkers [13:30]
- Data shows fasting for 14 hours is when you start seeing benefits [15:15]
Blood Sugar and Fasting [15:40]
- Blood sugar, like cigarette smoke, can accelerate aging [16:15]
Mechanistic Target of Rapamycin (MTOR) and Fasting [17:08]
- Restricting protein and the amino acid leucine [17:25]
- MTOR accelerates aging [17:58]
- Animal proteins stimulate MTOR [18:40]
- An all-vegetarian or an all-meat diet is not the answer [20:24]
Plant Phytonutrients [21:38]
- Phytoalexins [22:34]
Wisdom of nature [24:00]
Questions from the community [25:39]
- Keeping muscle tone after menopause [25:50]
- Sarcopenia: loss of muscle mass due to aging [26:40]
- Supplements for sarcopenia [28:05]
- Using plant proteins [29:33]

Resources to topics mentioned in this episode:

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Wednesday Oct 28, 2020

Conversation on COVID-19 with Dr. Robert Rountree and Dr. Frank Lipman

Wednesday Oct 28, 2020

Two renowned physicians – Dr. Robert Rountree, MD, and Dr. Frank Lipman, MD – joined us to discuss how their medical practices are being affected by COVID-19. They also give recommendations for managing stress, nutritional supplements to consider, the important of maintaining gut health, advice for consumers, and more.

Tuesday Oct 27, 2020

Sports Nutrition Expert, Joel Totoro

Tuesday Oct 27, 2020

Registered dietitian Joel Totoro speaks with host Dr. Alan Miller about his experiences as the first full-time sports dietitian in professional sports, as well as his connections to NCAA athletes, NFL football, and the state of nutrition in sport.